prevalence of hepatitis g virus (hgv) in high-risk groups and blood donors in tehran, iran
نویسندگان
چکیده
the hepatitis g virus (hgv) is a newly discovered rna virus, which is associated with acute or chronic hepatitis. a survey was conducted in thalassemic patients, intravenous drug users (ivdu) and blood donors aiming to investigate the prevalence of hepatitis g virus (hgv) infection in these groups in tehran. the presence of hgv rna in these populations was determined using reverse transcriptase polymerase chain reaction (rt-pcr) of the 5’ non-coding region (ncr) of the virus. one percent of blood donors, 12.9% of thalassemics and 8.8% of the ivdus, were infected with hgv. twenty-five percent of hgv positive cases were also positive for hcv and none were positive for hbv-dna. the greatest proportion of hcv positive cases were seen in ivdu group (67.4%) being the only hiv positive group (8.8%). in conclusion our study showed that hgv infection occurs with relatively intermediate frequency among thalassemics and ivdus in iran and a higher rate of hgv-rna was observed in older ivdus.
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عنوان ژورنال:
iranian journal of public healthجلد ۳۴، شماره ۴، صفحات ۴۱-۴۶
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